Analysis of the Epidemiological Profile of Glioblastomas in Brazil Between 2012 and 2021: evidence and challenges for public health

Análise do Perfil Epidemiológico de Glioblastomas no Brasil entre 2012 e 2021: evidências e desafios para a saúde pública

  • Christiane Nazareth Silva (1)    Christiane Nazareth Silva (1)
  • Marcelo Henrique Ribeiro Amoroso (2)    Marcelo Henrique Ribeiro Amoroso (2)
  • Anyelle Amaro Sousa (3)    Anyelle Amaro Sousa (3)
  • Letícia Gomes Alves (4)    Letícia Gomes Alves (4)
  • Marco Antônio Ribeiro Amoroso (5)    Marco Antônio Ribeiro Amoroso (5)
  • Daniel Sousa Amaro (6)    Daniel Sousa Amaro (6)
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Introdução: O glioblastoma é o tumor maligno primário do sistema nervoso central mais frequente. Ademais, esse tumor possui elevada morbimortalidade. Destarte, é necessário compreender a população que é mais acometida por essa patologia. Objetivo: Analisar o perfil epidemiológico das internações hospitalares por glioblastoma, no Brasil, durante o período de 2012 a 2021. Métodos: Estudo transversal retrospectivo de abordagem quantitativa, com coleta realizada no banco de dados do Sistema de Registro Hospitalar de Câncer (SisRHC).


Epidemiologia; Glioblastoma; Glioma; Neurocirurgia; Oncologia


Introduction: Glioblastoma is the most common primary malignant tumor of the central nervous system. Furthermore, this tumor has a high morbidity and mortality rate. It is therefore necessary to understand the population that is most affected by this pathology. Objective: To analyze the epidemiological profile of hospital admissions for glioblastoma in Brazil between 2012 and 2021. Methods: A retrospective cross-sectional study with a quantitative approach, with data collected from the Hospital Cancer Registry System (SisRHC) database. Results: 13,764 cases of hospitalization for glioblastoma were found, of which 7,927 were male and 5,756 were female. The approximate prevalence was 6.04 per 100,000 inhabitants. However, the geographical distribution was heterogeneous between the Brazilian Federative Units (FU). Approximately 73.9% of patients with this pathology were over 50 years old. Conclusion: Brazil has a prevalence similar to that found in other countries. Furthermore, the distribution among the UFs was mainly due to restricted access to neurology and neurosurgery services. Thus, a predominance of male cases was observed to the detriment of female cases. The incidence of glioblastomas increases after the age of 50, with a peak between 55 and 65. In addition, it was found that there is a higher prevalence among white people when compared to other ethnic groups. In terms of pathology, the frontal, parietal and temporal lobes were the most frequent primary locations. As for treatment, the most widely used approach in the country is radiotherapy in monotherapy and the most common outcome was death.


Epidemiology; Glioblastoma; Glioma; Neurosurgery; Oncology


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1MS, Medicine Student, Centro Universitário de Brasília, Liga Acadêmica de Neurociências do UniCEUB – LIANU, Brasília, DF, Brazil.

2MS, Medicine Student, Centro Universitário do Planalto Central Apparecido dos Santos, Brasília, DF, Brazil.

3MD, Graduated at Escola Superior de Ciências da Saúde, Brasília, DF, Brazil.

4MS, Medicine Student, Instituto Tocantinense Presidente Antônio Carlos – ITPAC, Porto Nacional, TO, Brazil.

5MD, Graduated at Centro Universitário de Brasília, Brasília, DF, Brazil.

6PhD in Molecular Pathology, Centro Universitário de Brasília, Brasília, DF, Brazil.


Received Nov 12, 2023

Accepted Jan 14, 2024

JBNC  Brazilian Journal of Neurosurgery

  •   ISSN (print version): 0103-5118
  •   e-ISSN (online version): 2446-6786


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